{"id":466,"date":"2018-04-11T06:15:58","date_gmt":"2018-04-11T06:15:58","guid":{"rendered":"http:\/\/fochon.wpengine.com\/?page_id=466"},"modified":"2018-05-05T05:51:44","modified_gmt":"2018-05-05T05:51:44","slug":"saf-189s","status":"publish","type":"page","link":"https:\/\/fochonpharma.com\/zh-hans\/what-we-do\/saf-189s\/","title":{"rendered":"SAF-189"},"content":{"rendered":"<p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h1>SAF-189<\/h1>\n<p><strong>SAF-189<\/strong>\u662f\u590d\u521b\u81ea\u4e3b\u5f00\u53d1\u7684\u3001\u5177\u6709\u53e3\u670d\u6d3b\u6027\u3001\u9ad8\u6548\u53ca\u9776\u5411\u9009\u62e9\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08ALK\uff09\u548c ROS \u539f\u764c\u57fa\u56e0\uff08ROS1\uff09\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597ALK\u9633\u6027\u6216ROS1 \u9633\u6027\u7684NSCLC\u3002ALK\u548cROS1\u57fa\u56e0\u91cd\u6392\u662f\u665a\u671fNSCLC\u4e9a\u7ec4\u91cd\u8981\u7684\u9884\u6d4b\u6027\u751f\u7269\u6807\u5fd7\u7269\u548c\u81f4\u764c\u9a71\u52a8\u56e0\u5b50\u3002<\/p>\n<p>\u4e0e\u5df2\u4e0a\u5e02\u7684ALK \/ROS1\u6291\u5236\u5242\u76f8\u6bd4\uff0cSAF-189\u5728\u4f53\u5185\u548c\u4f53\u5916\u6291\u5236ALK\/ROS1\u7684\u6fc0\u6d3b\u548c\u8010\u836f\u6027\u7a81\u53d8\u8868\u73b0\u51fa\u5f88\u5f3a\u7684<\/p>\n<p>\u836f\u6548\uff0c\u5177\u6709\u4f18\u5f02\u7684\u6297\u80bf\u7624\u4f5c\u7528\uff0c\u9ad8\u5ea6\u9776\u5411\u4e8e\u8111\u3001\u80ba\u548c\u80bf\u7624\u7ec4\u7ec7\uff0c\u5e76\u4e14\u5177\u6709\u826f\u597d\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u548c\u5b89\u5168\u6027\u3002<\/p>\n<p>\u5728\u6b63\u5728\u4e2d\u56fd\u8fdb\u884c\u7684Ib\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u4e0e\u6279\u51c6\u7684ALK\u6291\u5236\u5242\u76f8\u6bd4\uff0cSAF-189\u5728Crizotinib\u8010\u836f\u60a3\u8005\uff08\u542b\u8111\u8f6c\u79fb\uff09\u4e0a\u663e\u793a\u51fa\u836f\u6548\u63d0\u9ad8\u548c\u826f\u597d\u7684\u5b89\u5168\u6027\u3002 \u6211\u4eec\u76f8\u4fe1\uff0c\u6839\u636e\u4f18\u79c0\u7684\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u6570\u636e\uff0cSAF-189\u6709\u671b\u6210\u4e3a\u540c\u7cfb\u5217\u6700\u4f73\u7684\u9776\u5411ALK\u9633\u6027\u6216ROS1\u9633\u6027\u8f6c\u79fb\u6027NSCLC\u7684\u6291\u5236\u5242\u3002<\/p>\n<p>\u6211\u4eec\u8ba1\u5212\u5229\u7528SAF-189\u5728\u4e2d\u56fd\u7684\u4e34\u5e8a\u9a8c\u8bc1\u6570\u636e\u6765\u786e\u5b9a\u5168\u7403\u5408\u4f5c\u4f19\u4f34\uff0c\u5171\u540c\u5f00\u5c55\u4e34\u5e8a\u7814\u7a76\u7684\u63a8\u8fdb\u548c\u540e\u7eed\u5546\u4e1a\u5316\u7684\u5f00\u53d1\u3002<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image media=&#8221;935&#8243; 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